Input interpretation
fatty acid beta-oxidation II (core pathway) (human metabolic pathway)
Alternate name
fatty acid degradation
Pathway topology
Pathway topology
Pathway components
| 3-oxoacyl-CoA | RCOCH2CO-CoA | 3-oxoacyl-CoA | beta-ketoacyl-CoA | | | | an acyl-CoA | fatty acyl thioester-CoA | an acyl-CoA | RCH2CH2CO-CoA | acyl-Coenzyme A | | | | a 2, 3, 4-saturated fatty acyl CoA | | | | a (3S)-3-hydroxyacyl-CoA | a (S)-3-hydroxyacyl-CoA | a trans-3-hydroxyacyl-CoA | a 3-OH-acyl-CoA | a 3-hydroxyacyl-CoA | an L-3-hydroxyacyl-CoA | | | | a trans-2-enoyl-CoA | trans-2, 3-didehydroacyl-CoA | trans-2, 3-dehydroacyl-CoA | 2-enoyl-CoA | trans-didehydroacyl-CoA | | | | a fatty acid | | |
Pathway steps
| reaction ⟶ | + coenzyme A ⟶ + acetyl-CoA | 3-ketoacyl-CoA thiolase, mitochondrial | 3-ketoacyl-CoA thiolase, peroxisomal precursor | 3-ketoacyl-CoA thiolase ⟶ | + oxygen ⟶ + H_2 | acyl-coenzyme A oxidase 1, peroxisomal | acyl-coenzyme A oxidase 3, peroxisomal | acyl-coenzyme A oxidase 2, peroxisomal | acyl-coenzyme A oxidase peroxisomal ⟶ | + NAD+ ⟶ + NADH | 3-hydroxyacyl-CoA dehydrogenase type II | 3-hydroxyacyl-CoA dehydrogenase | short chain 3-hydroxyacyl-CoA dehydrogenase, mitochondrial precursor | long chain 3-hydroxyacyl-CoA dehydrogenase ⟶ | + H_2O ⟶ | enoyl-CoA hydratase, mitochondrial precursor | enoy CoA hydratase | enoyl-CoA hydratase | long-chain enoyl-CoA hydratase | enoyl CoA hydratase mitochondrial precursor ⟶ | + ATP + coenzyme A ⟶ + AMP + diphosphate | acetyl-coenzyme A synthetase 3 | fatty-acid-coenzyme A ligase, long-chain 6 | long-chain-fatty-acid--CoA ligase 4 | long-chain-fatty-acid--CoA ligase 5 | long chain fatty acid CoA ligase | long-chain-fatty-acid--CoA ligase 2 | long-chain-fatty-acid--CoA ligase 3
Related pathways
| overlapping components fatty acid beta-oxidation IV (unsaturated, even number) |