Input interpretation
![glycine](../image_source/53bf9e39e99595ab350024a86893754f.png)
glycine
Chemical names and formulas
![formula | NH_2CH_2COOH Hill formula | C_2H_5NO_2 name | glycine IUPAC name | 2-aminoacetic acid alternate names | acetic acid, amino- | aciport | glycocoll mass fractions | C (carbon) 32% | H (hydrogen) 6.71% | N (nitrogen) 18.7% | O (oxygen) 42.6%](../image_source/938c7af87e80daf2bb9532df2516b0a4.png)
formula | NH_2CH_2COOH Hill formula | C_2H_5NO_2 name | glycine IUPAC name | 2-aminoacetic acid alternate names | acetic acid, amino- | aciport | glycocoll mass fractions | C (carbon) 32% | H (hydrogen) 6.71% | N (nitrogen) 18.7% | O (oxygen) 42.6%
Lewis structure
![Draw the Lewis structure of glycine. Start by drawing the overall structure of the molecule, ignoring potential double and triple bonds: Count the total valence electrons of the carbon (n_C, val = 4), hydrogen (n_H, val = 1), nitrogen (n_N, val = 5), and oxygen (n_O, val = 6) atoms: 2 n_C, val + 5 n_H, val + n_N, val + 2 n_O, val = 30 Calculate the number of electrons needed to completely fill the valence shells for carbon (n_C, full = 8), hydrogen (n_H, full = 2), nitrogen (n_N, full = 8), and oxygen (n_O, full = 8): 2 n_C, full + 5 n_H, full + n_N, full + 2 n_O, full = 50 Subtracting these two numbers shows that 50 - 30 = 20 bonding electrons are needed. Each bond has two electrons, so in addition to the 9 bonds already present in the diagram add 1 bond. To minimize formal charge carbon wants 4 bonds and oxygen wants 2 bonds. Identify the atoms that want additional bonds and the number of electrons remaining on each atom: Fill in the 1 bond by pairing electrons between adjacent highlighted atoms: Answer: | |](../image_source/d64c787b838fb0381c88189742362ccc.png)
Draw the Lewis structure of glycine. Start by drawing the overall structure of the molecule, ignoring potential double and triple bonds: Count the total valence electrons of the carbon (n_C, val = 4), hydrogen (n_H, val = 1), nitrogen (n_N, val = 5), and oxygen (n_O, val = 6) atoms: 2 n_C, val + 5 n_H, val + n_N, val + 2 n_O, val = 30 Calculate the number of electrons needed to completely fill the valence shells for carbon (n_C, full = 8), hydrogen (n_H, full = 2), nitrogen (n_N, full = 8), and oxygen (n_O, full = 8): 2 n_C, full + 5 n_H, full + n_N, full + 2 n_O, full = 50 Subtracting these two numbers shows that 50 - 30 = 20 bonding electrons are needed. Each bond has two electrons, so in addition to the 9 bonds already present in the diagram add 1 bond. To minimize formal charge carbon wants 4 bonds and oxygen wants 2 bonds. Identify the atoms that want additional bonds and the number of electrons remaining on each atom: Fill in the 1 bond by pairing electrons between adjacent highlighted atoms: Answer: | |
3D structure
![3D structure](../image_source/34095f0a0e080e45bbc01c7ad2f4f59f.png)
3D structure
Basic properties
![molar mass | 75.07 g/mol phase | solid (at STP) melting point | 240 °C boiling point | 181 °C density | 1.64 g/cm^3](../image_source/6ae0042c430b0001059bc41c7a95d564.png)
molar mass | 75.07 g/mol phase | solid (at STP) melting point | 240 °C boiling point | 181 °C density | 1.64 g/cm^3
Units
Hydrophobicity and permeability properties
![experimental LogP hydrophobicity | -3.4 predicted LogP hydrophobicity | -3.33 predicted LogS | 0.87](../image_source/c48d47c54831573ee4b08099362d7376.png)
experimental LogP hydrophobicity | -3.4 predicted LogP hydrophobicity | -3.33 predicted LogS | 0.87
Basic drug properties
![approval status | approved | nutraceutical | small molecule drug categories | dietary supplement | glycine agent | micronutrient | non-essential amino acid dosage forms | irrigation: liquid | intraperitoneal: solution](../image_source/38f877d4ecc43d7c5cc2c169e42e81eb.png)
approval status | approved | nutraceutical | small molecule drug categories | dietary supplement | glycine agent | micronutrient | non-essential amino acid dosage forms | irrigation: liquid | intraperitoneal: solution
![brand names | aciport | glicoamin | glycocoll | glycolixir | glycosthene | gyn-hydralin | padil](../image_source/1fc9ce51aede81b78df1b5b00992e270.png)
brand names | aciport | glicoamin | glycocoll | glycolixir | glycosthene | gyn-hydralin | padil
Amino acid properties
![three-letter code | Gly one-letter code | G isoelectric point | 6.06 pK_a (α-COOH, (α-NH_3)^+) | 2.35 | 9.78 polarity | nonpolar codons | GGU | GGC | GGA | GGG occurrence in human proteins | 6.91%](../image_source/a0db81957435c18dab533f6bdee095a9.png)
three-letter code | Gly one-letter code | G isoelectric point | 6.06 pK_a (α-COOH, (α-NH_3)^+) | 2.35 | 9.78 polarity | nonpolar codons | GGU | GGC | GGA | GGG occurrence in human proteins | 6.91%
Solid properties (at STP)
![density | 1.64 g/cm^3 vapor pressure | 0.012 mmHg](../image_source/bbe7d0e0b0fb4c05c7ea7af3684ec305.png)
density | 1.64 g/cm^3 vapor pressure | 0.012 mmHg
Units
Thermodynamic properties
![specific heat of formation Δ_fH° | gas | -5.223 kJ/g | solid | -7.04 kJ/g molar heat of formation Δ_fH° | gas | -392.1 kJ/mol | solid | -528.5 kJ/mol molar heat of combustion | 974.1 kJ/mol | specific heat of combustion | 12.98 kJ/g | critical temperature | 660 K | critical pressure | 6.26 MPa | (at STP)](../image_source/433c74c0791ec233df18a48461519458.png)
specific heat of formation Δ_fH° | gas | -5.223 kJ/g | solid | -7.04 kJ/g molar heat of formation Δ_fH° | gas | -392.1 kJ/mol | solid | -528.5 kJ/mol molar heat of combustion | 974.1 kJ/mol | specific heat of combustion | 12.98 kJ/g | critical temperature | 660 K | critical pressure | 6.26 MPa | (at STP)
Chemical identifiers
![CAS number | 56-40-6 Beilstein number | 635782 PubChem CID number | 750 PubChem SID number | 3339 SMILES identifier | C(C(=O)O)N InChI identifier | InChI=1/C2H5NO2/c3-1-2(4)5/h1, 3H2, (H, 4, 5)/f/h4H InChI key | DHMQDGOQFOQNFH-JLSKMEETCN RTECS number | MB7600000 MDL number | MFCD00008131](../image_source/9e5ae80d1cac6eaac135fa2a98b51881.png)
CAS number | 56-40-6 Beilstein number | 635782 PubChem CID number | 750 PubChem SID number | 3339 SMILES identifier | C(C(=O)O)N InChI identifier | InChI=1/C2H5NO2/c3-1-2(4)5/h1, 3H2, (H, 4, 5)/f/h4H InChI key | DHMQDGOQFOQNFH-JLSKMEETCN RTECS number | MB7600000 MDL number | MFCD00008131
NFPA label
![NFPA label](../image_source/0777dc1ff3ebb2f539d689fd7ba5e6a9.png)
NFPA label
![NFPA health rating | 1 NFPA fire rating | 0 NFPA reactivity rating | 0](../image_source/bdcba0711f14327df7e9a85cd4fda487.png)
NFPA health rating | 1 NFPA fire rating | 0 NFPA reactivity rating | 0
Safety properties
![flash point | 99.5 °C](../image_source/ae7c9f278a5eb77d6139e67388dcb7f4.png)
flash point | 99.5 °C
Toxicity properties
![RTECS classes | mutagen](../image_source/351094e2737bcf0b2b370523b1d6094f.png)
RTECS classes | mutagen