Input interpretation
lysine degradation IV (human metabolic pathway)
Alternate names
delta-aminovalerate pathway | delta-aminovaleric acid pathway
Pathway topology
Pathway topology
Pathway components
| L-lysine | (2S)-2, 6-diaminohexanoic acid | aminutrin | (S)-2, 6-diaminocaproic acid | 146.2 g/mol | | H_2N(CH_2)_4CH(NH_2)CO_2H | 5-aminopentanamide | 5-aminovaleramide | delta-aminovaleramide | 116.2 g/mol | | C_5H_12N_2O_1 | 5-aminovaleric acid | 5-amino-N-valeric acid | 5-aminopentanoic acid | homopiperidinic acid | valeric acid, 5-amino- | 117.1 g/mol | | NH_2(CH_2)_4CO_2H | glutarate semialdehyde | 5-oxopentanoate | 116.1 g/mol | | C_5H_8O_3 | glutaric acid | 1, 3-propanedicarboxylic acid | 1, 5-pentanedioic acid | pentandioic acid | pentanedioic acid | 132.1 g/mol | | HOOC(CH_2)_3COOH | glutaryl-CoA | glutaryl-coenzyme A | 881.6 g/mol | | C_26H_42N_7O_19P_3S_1
Pathway steps
| reaction ⟶ | + oxygen ⟶ + CO_2 + H_2O | (none) ⟶ | + H_2O ⟶ + ammonia | (none) ⟶ | + 2-ketoglutarate ⟶ + L-glutamate | (none) ⟶ | + NADP+ + H_2O ⟶ + NADPH + H+ | (none) ⟶ | + coenzyme A ⟶ | (none)
Related pathways
| overlapping components lysine degradation III | glutaryl-CoA degradation | benzoyl-CoA degradation II (anaerobic) | lysine fermentation to acetate and butyrate |