Input interpretation
fatty acid beta-oxidation IV (unsaturated, even number) (human metabolic pathway)
Pathway topology
Pathway topology
Pathway components
| a 2cis-dienoyl-CoA | | | | a trans-3-enoyl-CoA | | | | a trans-2-enoyl-CoA | trans-2, 3-didehydroacyl-CoA | trans-2, 3-dehydroacyl-CoA | 2-enoyl-CoA | trans-didehydroacyl-CoA | | | | a (3S)-3-hydroxyacyl-CoA | a (S)-3-hydroxyacyl-CoA | a trans-3-hydroxyacyl-CoA | a 3-OH-acyl-CoA | a 3-hydroxyacyl-CoA | an L-3-hydroxyacyl-CoA | | | | a cis-2-enoyl-CoA | | | | an (R)-3-hydroxyacyl-CoA | a D-3-hydroxyacyl-CoA | an (R)-hydroxyacyl-CoA | a cis-3-hydroxyacyl-CoA | a 3-OH-acyl-CoA | a 3-hydroxyacyl-CoA | | |
Pathway steps
| reaction ⟶ | + NADPH ⟶ + NADP+ | 2, 4-dienoyl-CoA reductase, mitochondrial precursor | peroxisomal 2, 4-dienoyl-CoA reductase ⟶ | ⟶ | (none) ⟶ | + H_2O ⟶ | enoyl-CoA hydratase, mitochondrial precursor | enoy CoA hydratase | enoyl-CoA hydratase | long-chain enoyl-CoA hydratase | enoyl CoA hydratase mitochondrial precursor ⟶ | + H_2O ⟶ | (none) ⟶ | ⟶ + H_2O | (none) ⟶ | ⟶ | 3-hydroxybutyryl-CoA epimerase
Related pathways
| overlapping components fatty acid beta-oxidation II (core pathway) |