Input interpretation
lactate oxidation (human metabolic pathway)
Pathway topology
Pathway topology
Pathway components
| L-(+)-lactic acid | (2S)-2-hydroxypropanoic acid | espiritin | lactic acid | paralactic acid | (S)-(+)-2-hydroxypropanoic acid | (S)-2-hydroxypropionic acid sodium salt | (S)-(+)-lactic acid | 90.1 g/mol | | CH_3CH(OH)CO_2H | pyruvic acid | α-ketopropionic acid | 88.1 g/mol | | CH_3COCOOH | acetyl-CoA | acetyl coenzyme-A | ac-CoA | acetylcoenzyme-A | acetyl-S-CoA | ac-S-CoA | 809.6 g/mol | | C_23H_38N_7O_17P_3S_1 | acetylphosphate | 140 g/mol | | C_2H_5O_5P | acetic acid | acetic acid, glacial | ethanoic acid | ethylic acid | glacial acetic acid | methanecarboxylic acid | vinegar acid | 60.1 g/mol | | CH_3CO_2H
Pathway steps
| reaction ⟶ | + NAD+ ⟶ + NADH | L-lactate dehydrogenase chain | L-lactate dehydrogenase A-like | L-lactate dehydrogenase B chain | L-lactate dehydrogenase C chain | L-lactate dehydrogenase A chain ⟶ | + coenzyme A + NAD+ ⟶ + CO_2 + NADH | pyruvate dehydrogenase E1 component beta subunit, mitochondrial precursor | dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor | pyruvate dehydrogenase protein X component, mitochondrial precursor ⟶ | + phosphate ⟶ + coenzyme A | (none) ⟶ | + ADP ⟶ + ATP | (none)
Related pathways
| overlapping components mixed acid fermentation | lysine fermentation to acetate and butyrate | Entner-Doudoroff pathway II (non-phosphorylative) | TCA cycle | degradation of pyrimidine deoxyribonucleosides | purine deoxyribonucleosides degradation |