Input interpretation
![L-threonine](../image_source/f3ffa2a49dba0946594b17fd1d2b1919.png)
L-threonine
Chemical names and formulas
![formula | C_4H_9NO_3 name | L-threonine IUPAC name | (2S, 3R)-2-azaniumyl-3-hydroxy-butanoate alternate names | 2-amino-3-hydroxybutanoic acid | L-alpha-amino-beta-hydroxybutyric acid mass fractions | C (carbon) 40.3% | H (hydrogen) 7.62% | N (nitrogen) 11.8% | O (oxygen) 40.3%](../image_source/2164588babf80e83b7d410b5b8200579.png)
formula | C_4H_9NO_3 name | L-threonine IUPAC name | (2S, 3R)-2-azaniumyl-3-hydroxy-butanoate alternate names | 2-amino-3-hydroxybutanoic acid | L-alpha-amino-beta-hydroxybutyric acid mass fractions | C (carbon) 40.3% | H (hydrogen) 7.62% | N (nitrogen) 11.8% | O (oxygen) 40.3%
Lewis structure
![Draw the Lewis structure of L-threonine. Start by drawing the overall structure of the molecule, ignoring potential double and triple bonds: Count the total valence electrons of the carbon (n_C, val = 4), hydrogen (n_H, val = 1), nitrogen (n_N, val = 5), and oxygen (n_O, val = 6) atoms: 4 n_C, val + 9 n_H, val + n_N, val + 3 n_O, val = 48 Calculate the number of electrons needed to completely fill the valence shells for carbon (n_C, full = 8), hydrogen (n_H, full = 2), nitrogen (n_N, full = 8), and oxygen (n_O, full = 8): 4 n_C, full + 9 n_H, full + n_N, full + 3 n_O, full = 82 Subtracting these two numbers shows that 82 - 48 = 34 bonding electrons are needed. Each bond has two electrons, so in addition to the 16 bonds already present in the diagram add 1 bond. To minimize formal charge carbon wants 4 bonds and oxygen wants 2 bonds. Identify the atoms that want additional bonds and the number of electrons remaining on each atom: Fill in the 1 bond by pairing electrons between adjacent highlighted atoms: Answer: | |](../image_source/c20e4a1caaf21cca3e3a8346c66f59d1.png)
Draw the Lewis structure of L-threonine. Start by drawing the overall structure of the molecule, ignoring potential double and triple bonds: Count the total valence electrons of the carbon (n_C, val = 4), hydrogen (n_H, val = 1), nitrogen (n_N, val = 5), and oxygen (n_O, val = 6) atoms: 4 n_C, val + 9 n_H, val + n_N, val + 3 n_O, val = 48 Calculate the number of electrons needed to completely fill the valence shells for carbon (n_C, full = 8), hydrogen (n_H, full = 2), nitrogen (n_N, full = 8), and oxygen (n_O, full = 8): 4 n_C, full + 9 n_H, full + n_N, full + 3 n_O, full = 82 Subtracting these two numbers shows that 82 - 48 = 34 bonding electrons are needed. Each bond has two electrons, so in addition to the 16 bonds already present in the diagram add 1 bond. To minimize formal charge carbon wants 4 bonds and oxygen wants 2 bonds. Identify the atoms that want additional bonds and the number of electrons remaining on each atom: Fill in the 1 bond by pairing electrons between adjacent highlighted atoms: Answer: | |
3D structure
![3D structure](../image_source/bfe785fa3cd2f5154fd852d6b4dee24a.png)
3D structure
Basic properties
![molar mass | 119.12 g/mol phase | solid (at STP) melting point | 136 °C boiling point | 260 °C density | 1.464 g/cm^3](../image_source/bd696e37704f7196e74aa70b2677ed3b.png)
molar mass | 119.12 g/mol phase | solid (at STP) melting point | 136 °C boiling point | 260 °C density | 1.464 g/cm^3
Units
Hydrophobicity and permeability properties
![experimental LogP hydrophobicity | -3.5 predicted LogP hydrophobicity | -3 experimental LogS | -0.09 predicted LogS | 0.6](../image_source/6a606a594043197b8ec7056fb9e260f1.png)
experimental LogP hydrophobicity | -3.5 predicted LogP hydrophobicity | -3 experimental LogS | -0.09 predicted LogS | 0.6
Basic drug properties
![approval status | approved | nutraceutical | small molecule drug categories | dietary supplement | essential amino acid | micronutrient](../image_source/0b531009a4516c5008fb3379f876738e.png)
approval status | approved | nutraceutical | small molecule drug categories | dietary supplement | essential amino acid | micronutrient
Amino acid properties
![three-letter code | Thr one-letter code | T isoelectric point | 5.6 pK_a (α-COOH, (α-NH_3)^+) | 2.09 | 9.1 polarity | polar codons | ACU | ACC | ACA | ACG occurrence in human proteins | 5.77%](../image_source/96ed276b2ddcb0c18ba630b1dfcb721b.png)
three-letter code | Thr one-letter code | T isoelectric point | 5.6 pK_a (α-COOH, (α-NH_3)^+) | 2.09 | 9.1 polarity | polar codons | ACU | ACC | ACA | ACG occurrence in human proteins | 5.77%
Solid properties (at STP)
![density | 1.464 g/cm^3](../image_source/fa3e7643e91a8d880aefeb968614a98f.png)
density | 1.464 g/cm^3
Units
Thermodynamic properties
![specific heat of formation Δ_fH° | solid | -6.776 kJ/g molar heat of formation Δ_fH° | solid | -807.2 kJ/mol critical temperature | 711 K | critical pressure | 5.5 MPa | (at STP)](../image_source/4cc4869fcf89eb421d1da8f5a9e096a5.png)
specific heat of formation Δ_fH° | solid | -6.776 kJ/g molar heat of formation Δ_fH° | solid | -807.2 kJ/mol critical temperature | 711 K | critical pressure | 5.5 MPa | (at STP)
Chemical identifiers
![CAS number | 72-19-5 Beilstein number | 1721646 PubChem CID number | 6971019 PubChem SID number | 3488 SMILES identifier | CC(C(C(=O)[O-])[NH3+])O InChI identifier | InChI=1/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3, 6H, 5H2, 1H3, (H, 7, 8)/t2-, 3+/m1/s1/f/h5H InChI key | AYFVYJQAPQTCCC-QYISKGLTDV EU number | 200-774-1 RTECS number | XO8590000 NSC number | 46701](../image_source/dc4087e01a140640789aa2d8920d623c.png)
CAS number | 72-19-5 Beilstein number | 1721646 PubChem CID number | 6971019 PubChem SID number | 3488 SMILES identifier | CC(C(C(=O)[O-])[NH3+])O InChI identifier | InChI=1/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3, 6H, 5H2, 1H3, (H, 7, 8)/t2-, 3+/m1/s1/f/h5H InChI key | AYFVYJQAPQTCCC-QYISKGLTDV EU number | 200-774-1 RTECS number | XO8590000 NSC number | 46701
Toxicity properties
![RTECS classes | mutagen](../image_source/47ba5a5dab3df4a1aa22a01e262a950d.png)
RTECS classes | mutagen