Input interpretation
adenosylcobalamin salvage from cobinamide and cobalamin (human metabolic pathway)
Alternate name
vitamin B12 biosynthesis
Pathway topology
Pathway topology
Pathway components
| adenosine triphosphate | adenosine 5'-(tetrahydrogen triphosphate) | 507.2 g/mol | | C_10H_16N_5O_13P_3 | cobinamide | Cbi | cobyrinic acid a, c-diamide | 990.1 g/mol | | C_48H_72N_11O_8Co_1 | adenosylcobinamide | 1240 g/mol | | C_58H_84N_16O_11Co_1 | 5, 6-dimethylbenzimidazole | 5, 6-dimethyl-1H-benzimidazole | benzimidazole, 5, 6-dimethyl- | dimedazole | dimezol | 146.2 g/mol | | C_9H_10N_2 | namn | 335.2 g/mol | | C_11H_14NO_9P | alpha-ribazole-5'-P | N1-(5'-phospho-alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | DMB-ribose-5'-P | 358.3 g/mol | | C_14H_19N_2O_7P_1 | adenosyl-cobinamide phosphate | adenosylcobinamide-P | 1318 g/mol | | C_58H_83N_16O_14P_1Co_1 | alpha-ribazole | N1-(alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | 278.3 g/mol | | C_14H_18N_2O_4 | adenosylcobinamide-GDP | Adenosine-GDP-cobinamide | 1664 g/mol | | C_68H_95N_21O_21P_2Co_1 | coenzyme B12 | adenosylcobalamin | cobamide coenzyme | deoxyadenosylcobalamin | cobamamide | vitamin B12 | cobamamid | 5, 6-dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide | cobinamide, Co-(5'-deoxyadenosine-5') derivative hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole | (5'-deoxy-5'-adenosyl)cobamide coenzyme | (5, 6-dimethylbenzimidazolyl)cobamide coenzyme | a-(5, 6-dimethylbenzimidazolyl)cobamide coenzyme | 5'-deoxy-5'-adenosylcobalamin | 5'-deoxyadenosyl vitamin B12 | 5'-deoxyadenosyl-5, 6-dimethylbenzimidazolylcobamide | 5'-deoxyadenosylcobalamin | 5, 6-dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide | calomide | cobalamin coenzyme | cobalamin, Co-(5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5, 6-dimethyl-1H-benzimidazolyl)- | cobinamide, Co-(5'-deoxyadenosine-5') deriv., | cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosylbenzimidazole | DBC coenzyme | dibencozide | funacomide | 1581 g/mol | | C_72H_101N_18O_17P_1Co_1 | cob(I)alamin | B12 | cobalamin | vitamin B12 | Cbl | vitamin B12s | 1329 g/mol | | C_62H_88N_13O_14P_1Co_1
Pathway steps
| reaction + ⟶ | + ⟶ + PPPi | cob(I)alamin adenosyltransferase + ⟶ | + ⟶ + PPPi | (none) + ⟶ | + ⟶ + ADP | (none) + ⟶ | + ⟶ + nicotinate | (none) ⟶ | + H_2O ⟶ + phosphate | (none) ⟶ | + GTP ⟶ + diphosphate | (none) + ⟶ | + ⟶ + GMP | (none)
Related pathways
| overlapping components NAD biosynthesis I (from aspartate) | NAD salvage pathway I | NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde |