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adenosylcobalamin salvage from cobinamide and cobalamin

Input interpretation

adenosylcobalamin salvage from cobinamide and cobalamin (human metabolic pathway)
adenosylcobalamin salvage from cobinamide and cobalamin (human metabolic pathway)

Alternate name

vitamin B12 biosynthesis
vitamin B12 biosynthesis

Pathway topology

Pathway topology
Pathway topology

Pathway components

 | adenosine triphosphate | adenosine 5'-(tetrahydrogen triphosphate) | 507.2 g/mol  | | C_10H_16N_5O_13P_3  | cobinamide | Cbi | cobyrinic acid a, c-diamide | 990.1 g/mol  | | C_48H_72N_11O_8Co_1  | adenosylcobinamide | 1240 g/mol  | | C_58H_84N_16O_11Co_1  | 5, 6-dimethylbenzimidazole | 5, 6-dimethyl-1H-benzimidazole | benzimidazole, 5, 6-dimethyl- | dimedazole | dimezol | 146.2 g/mol  | | C_9H_10N_2  | namn | 335.2 g/mol  | | C_11H_14NO_9P  | alpha-ribazole-5'-P | N1-(5'-phospho-alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | DMB-ribose-5'-P | 358.3 g/mol  | | C_14H_19N_2O_7P_1  | adenosyl-cobinamide phosphate | adenosylcobinamide-P | 1318 g/mol  | | C_58H_83N_16O_14P_1Co_1  | alpha-ribazole | N1-(alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | 278.3 g/mol  | | C_14H_18N_2O_4  | adenosylcobinamide-GDP | Adenosine-GDP-cobinamide | 1664 g/mol  | | C_68H_95N_21O_21P_2Co_1  | coenzyme B12 | adenosylcobalamin | cobamide coenzyme | deoxyadenosylcobalamin | cobamamide | vitamin B12 | cobamamid | 5, 6-dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide | cobinamide, Co-(5'-deoxyadenosine-5') derivative hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole | (5'-deoxy-5'-adenosyl)cobamide coenzyme | (5, 6-dimethylbenzimidazolyl)cobamide coenzyme | a-(5, 6-dimethylbenzimidazolyl)cobamide coenzyme | 5'-deoxy-5'-adenosylcobalamin | 5'-deoxyadenosyl vitamin B12 | 5'-deoxyadenosyl-5, 6-dimethylbenzimidazolylcobamide | 5'-deoxyadenosylcobalamin | 5, 6-dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide | calomide | cobalamin coenzyme | cobalamin, Co-(5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5, 6-dimethyl-1H-benzimidazolyl)- | cobinamide, Co-(5'-deoxyadenosine-5') deriv., | cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosylbenzimidazole | DBC coenzyme | dibencozide | funacomide | 1581 g/mol  | | C_72H_101N_18O_17P_1Co_1  | cob(I)alamin | B12 | cobalamin | vitamin B12 | Cbl | vitamin B12s | 1329 g/mol  | | C_62H_88N_13O_14P_1Co_1
| adenosine triphosphate | adenosine 5'-(tetrahydrogen triphosphate) | 507.2 g/mol | | C_10H_16N_5O_13P_3 | cobinamide | Cbi | cobyrinic acid a, c-diamide | 990.1 g/mol | | C_48H_72N_11O_8Co_1 | adenosylcobinamide | 1240 g/mol | | C_58H_84N_16O_11Co_1 | 5, 6-dimethylbenzimidazole | 5, 6-dimethyl-1H-benzimidazole | benzimidazole, 5, 6-dimethyl- | dimedazole | dimezol | 146.2 g/mol | | C_9H_10N_2 | namn | 335.2 g/mol | | C_11H_14NO_9P | alpha-ribazole-5'-P | N1-(5'-phospho-alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | DMB-ribose-5'-P | 358.3 g/mol | | C_14H_19N_2O_7P_1 | adenosyl-cobinamide phosphate | adenosylcobinamide-P | 1318 g/mol | | C_58H_83N_16O_14P_1Co_1 | alpha-ribazole | N1-(alpha-D-ribosyl)-5, 6-dimethylbenzimidazole | 278.3 g/mol | | C_14H_18N_2O_4 | adenosylcobinamide-GDP | Adenosine-GDP-cobinamide | 1664 g/mol | | C_68H_95N_21O_21P_2Co_1 | coenzyme B12 | adenosylcobalamin | cobamide coenzyme | deoxyadenosylcobalamin | cobamamide | vitamin B12 | cobamamid | 5, 6-dimethylbenzimidazolyl-5-deoxyadenosyl-cobamide | cobinamide, Co-(5'-deoxyadenosine-5') derivative hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole | (5'-deoxy-5'-adenosyl)cobamide coenzyme | (5, 6-dimethylbenzimidazolyl)cobamide coenzyme | a-(5, 6-dimethylbenzimidazolyl)cobamide coenzyme | 5'-deoxy-5'-adenosylcobalamin | 5'-deoxyadenosyl vitamin B12 | 5'-deoxyadenosyl-5, 6-dimethylbenzimidazolylcobamide | 5'-deoxyadenosylcobalamin | 5, 6-dimethylbenzimidazolyl-Co-5'-deoxyadenosylcobamide | calomide | cobalamin coenzyme | cobalamin, Co-(5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5'-deoxy-5'-adenosyl)- | cobamide coenzyme, (5, 6-dimethyl-1H-benzimidazolyl)- | cobinamide, Co-(5'-deoxyadenosine-5') deriv., | cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, 3'-ester with 5, 6-dimethyl-1-a-D-ribofuranosylbenzimidazole | DBC coenzyme | dibencozide | funacomide | 1581 g/mol | | C_72H_101N_18O_17P_1Co_1 | cob(I)alamin | B12 | cobalamin | vitamin B12 | Cbl | vitamin B12s | 1329 g/mol | | C_62H_88N_13O_14P_1Co_1

Pathway steps

 | reaction  + ⟶ | + ⟶ + PPPi  | cob(I)alamin adenosyltransferase  + ⟶ | + ⟶ + PPPi  | (none)  + ⟶ | + ⟶ + ADP  | (none)  + ⟶ | + ⟶ + nicotinate  | (none)  ⟶ | + H_2O ⟶ + phosphate  | (none)  ⟶ | + GTP ⟶ + diphosphate  | (none)  + ⟶ | + ⟶ + GMP  | (none)
| reaction + ⟶ | + ⟶ + PPPi | cob(I)alamin adenosyltransferase + ⟶ | + ⟶ + PPPi | (none) + ⟶ | + ⟶ + ADP | (none) + ⟶ | + ⟶ + nicotinate | (none) ⟶ | + H_2O ⟶ + phosphate | (none) ⟶ | + GTP ⟶ + diphosphate | (none) + ⟶ | + ⟶ + GMP | (none)

Related pathways

 | overlapping components NAD biosynthesis I (from aspartate) |  NAD salvage pathway I |  NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde |
| overlapping components NAD biosynthesis I (from aspartate) | NAD salvage pathway I | NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde |